Article

Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

2025-02-19

Abstract excerpt

Gene expression is tightly controlled by DNA elements called enhancers by associating with lineage-specific transcription factors. These enhancers transcribe non-coding RNAs (called enhancer RNAs or eRNAs). eRNA expression is an early indicator of transcription factor activity and is associated with treatment response and survival in cancer patients. However, the attempts to identify prognostic eRNAs in breast can...

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Literature Corpus work: b7180127-85d8-55fc-ab1d-7cb6a3031c41
DOI: 10.1101/2025.02.18.638890

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