Article

Exogenous Prolactin Receptor Antagonism Attenuates Post-thyroidectomy Retching-like Behavior by Inhibiting Dopaminergic Neuronal Activation in the Nucleus Tractus Solitarius

2026-07-03

Abstract excerpt

<title>Abstract</title> <p> Background Postoperative nausea and vomiting (PONV) are significant clinical challenges, especially after thyroid surgery. Our previous research established a thyroidectomy-induced retching-like behavior (TIRB) mouse model and identified NLRP3 inflammasome-mediated neuroinflammation as a key contributor. Concurrently, transcriptomic analysis has revealed a significant upregulation of...

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Literature Corpus work: b6d5d9ba-19d1-5d21-8183-f337f02b0f63
DOI: 10.21203/rs.3.rs-10074696/v1

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Exogenous Prolactin Receptor Antagonism Attenuates Post-thyroidectomy Retching-like Behavior by Inhibiting Dopaminergic Neuronal Activation in the Nucleus Tractus SolitariusDOI 10.21203/rs.3.rs-10074696/v1Read

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