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Article

Molecular Dynamics in the Ventral Tegmental Area during Chronic Pain-Induced Negative Affect

2025-07-04

Abstract excerpt

Chronic pain frequently coexists with negative affect, with about 60% of patients suffering from both. This dual condition complicates treatment and exacerbates both disorders, highlighting the urgent need for innovative therapeutic strategies. Chronic pain negative affect (CPNA) involves complex neurobiological changes, including increased hyperexcitability of the ventral tegmental area (VTA), a critical region i...

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Literature Corpus work
3b7fed7a-820f-542b-8238-d9cb51afc5af
DOI
10.1101/2025.07.01.662604
Open publication

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Molecular Dynamics in the Ventral Tegmental Area during Chronic Pain-Induced Negative AffectDOI 10.1101/2025.07.01.662604
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