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Hinokitiol alters Gene Expression in <i>Aspergillus fumigatus</i> , protects against fungal keratitis by Reducing Fungal Load, LOX-1, Proinflammatory cytokines and Neutrophil Infiltration

2022-02-18

Abstract excerpt

Hinokitiol (HK), a tropolone-related compound found in cupressaceous plants, has antifungal and anti-inflammatory properties. But its roles in Aspergillus fumigatus ( A.F. ) keratitis remains unknown. This study examined the antifungal activity of HK against A.F. and investigated its possible mechanisms at the ultrastructural and transcriptional levels. We tested the minimum inhibitory concentration (MIC) of HK...

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Literature Corpus work
b69dc194-42d4-573a-8015-a75af7952200
DOI
10.1101/2022.02.18.480984
Open publication

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Hinokitiol alters Gene Expression in <i>Aspergillus fumigatus</i> , protects against fungal keratitis by Reducing Fungal Load, LOX-1, Proinflammatory cytokines and Neutrophil InfiltrationDOI 10.1101/2022.02.18.480984
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