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Bisphosphonates synergistically enhance the antifungal activity of azoles in dermatophytes and other pathogenic molds

2024-03-27

Abstract excerpt

Superficial infections of the skin, hair and nails by fungal dermatophytes are the most prevalent of human mycoses, and many infections are refractory to treatment. As current treatment options are limited, recent research has explored drug synergy with azoles for dermatophytoses. Bisphosphonates, which are approved to treat osteoporosis, can synergistically enhance the activity of azoles in diverse yeast pathogen...

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Literature Corpus work
757b9fd2-7489-5c30-9005-9f75f891b11f
DOI
10.1101/2024.03.25.586613
Open publication

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Bisphosphonates synergistically enhance the antifungal activity of azoles in dermatophytes and other pathogenic moldsDOI 10.1101/2024.03.25.586613
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