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From PEGylation to Next-Generation Polymers: Overcoming Biological Barriers – A Review

2026-01-21

Abstract excerpt

Poly(ethylene glycol) (PEG) has long stood as the prevailing standard in drug delivery, celebrated for its capacity to enhance solubility, extend circulation, and improve pharmacological performance. Nevertheless, the emergence of anti-PEG antibodies, accelerated clearance, and limited biodegradability increasingly undermine its role as a universal solution. In response, a new generation of polymers has been devel...

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Literature Corpus work
b6801eaf-d940-5232-ba4f-b8bf1605d0ba
DOI
10.20944/preprints202601.1511.v1
Open publication

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From PEGylation to Next-Generation Polymers: Overcoming Biological Barriers – A ReviewDOI 10.20944/preprints202601.1511.v1
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