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New ShK-Like Peptide from the Jellyfish <em>Nemopilema nomurai</em> Has Human Potassium Voltage-Gated Channel-Blocking Activity

2023-09-19

Abstract excerpt

We have identified a new human voltage-gated potassium channel (hKv1.3) blocker, NnK-1, in the jellyfish Nemopilema nomurai, based on its genomic information. The gene sequence encoding NnK-1 contains 5,408 base pairs, with five introns and six exons. The coding sequence of the NnK-1 precursor is 894 nucleotides long and encodes 297 amino acids, containing five presumptive ShK-like peptides. An electrophysiologica...

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Literature Corpus work
b61f94f1-01d0-5322-b16b-4e47b8f32425
DOI
10.20944/preprints202309.1253.v1
Open publication

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New ShK-Like Peptide from the Jellyfish <em>Nemopilema nomurai</em> Has Human Potassium Voltage-Gated Channel-Blocking ActivityDOI 10.20944/preprints202309.1253.v1
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