Article

Deciphering the Epigenetic Role of KDM4A in Pancreatic β-like Cell Differentiation from iPSCs

2025-05-20

Abstract excerpt

Pancreatic β cells derived from human induced pluripotent stem cells (hiPSCs) represent a promising therapeutic avenue in regenerative medicine for diabetes treatment. However, current differentiation protocols lack the specificity and efficiency required to reliably produce fully functional β cells, limiting their clinical applicability. Epigenetic barriers, such as histone modifications, may hinder proper differ...

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Literature Corpus work: b5f51915-086c-50a4-9e0c-2545113c3b10
DOI: 10.20944/preprints202505.1564.v1

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