Article

Metabolomic Response to Non-Steroidal Anti-Inflammatory Drugs

2024-12-02

Abstract excerpt

Non-steroidal anti-inflammatory drugs (NSAIDs) are popular choices for the mitigation of pain and inflammation; however, they are accompanied by side effects in the gastrointestinal and cardiovascular systems. We compared the effects of naproxen, a traditional NSAID, and celecoxib, a cyclooxygenase -2 (Cox-2) inhibitor, in humans. Our findings showed a decrease in tryptophan and kynurenine levels in plasma of volu...

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Literature Corpus work: b5e6a11c-6729-5a15-bb3e-042308b2f5ec
DOI: 10.1101/2024.11.26.625478

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