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cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequence

2023-04-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Sorafenib is a first-line chemotherapy drug for treating advanced hepatocellular carcinoma (HCC). However, its therapeutic effect has been seriously affected by the emergence of sorafenib resistance in HCC patients. The underlying mechanism of sorafenib resistance is unclear. Here, we report a circular RNA, cDCBLD2, which plays an important role in sorafenib resi...

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Literature Corpus work
b56d1e15-84e7-5ed3-b255-96940400fee1
DOI
10.21203/rs.3.rs-2795751/v1
Open publication

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cDCBLD2 mediates sorafenib resistance in hepatocellular carcinoma by sponging miR-345-5p binding to the TOP2A coding sequenceDOI 10.21203/rs.3.rs-2795751/v1
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