Article

HTR1D regulates the PI3K/Akt signaling pathway to impact hepatocellular carcinoma development and resistance to sorafenib

2024-06-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Hepatocellular carcinoma (HCC) is a form of cancer with high incidence rates and low survival rates worldwide. Oral sorafenib is a promising therapy for advanced HCC, but resistance to the drug limits its effectiveness. HTR1D, a gene that is highly expressed in HCC, plays a crucial role in the development, drug resistance, and prognosis of the disease.<bold>Metho...

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Literature Corpus work: 7351cd62-5936-5b78-a7f3-5658e14eecad
DOI: 10.21203/rs.3.rs-4447882/v1

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