Article

Extracellular Proximity Labeling Reveals an Expanded Interactome for the Matrisome Protein TIMP2

2024-01-15

Abstract excerpt

<title>Abstract</title> <p>Classical methods of investigating protein-protein interactions (PPIs) are generally performed in non-living systems, yet in recent years new technologies utilizing proximity labeling (PL) have given researchers the tools to explore proximal PPIs in living systems. PL has distinct advantages over traditional protein interactome studies, such as the ability to identify weak and transient...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b531914e-0591-589a-90bb-1ecb15637cbe
DOI: 10.21203/rs.3.rs-3857263/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Extracellular Proximity Labeling Reveals an Expanded Interactome for the Matrisome Protein TIMP2DOI 10.21203/rs.3.rs-3857263/v1Read

BioID2-Based Tau Interactome Reveals Novel and Known Protein Interactions Associated with Multiple Cellular PathwaysSemantic proximity Read

Single-Cell Protein Interactomes by the Proximity Network AssaySemantic proximity Read

The TIMP protein family: diverse roles in pathophysiologySemantic proximity Read

A Comprehensive Bioinformatics Analysis of TIMP2 in Multiple MalignanciesSemantic proximity Read

Whole Organism Profiling of the Timp Gene FamilySemantic proximity Read

Rapid interactome profiling by massive sequencingSemantic proximity Read

Advances in the proteomic profiling of the matrisome and adhesomeSemantic proximity Read

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP ComplexesSemantic proximity Read

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancerSemantic proximity Read

Spatial mapping of proteins and their activity states in cancer models by multiplex in situ PLASemantic proximity Read

Profiling protein expression and interactions: proximity ligation as a tool for personalized medicineSemantic proximity Read

Characterization of PROTAC specificity and endogenous protein interactomes using ProtacIDSemantic proximity Read