Article

ROR2 Promotes EMT and Necrosis by Hyperactivating ERK in Melanoma

2021-11-17

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>Receptor tyrosine kinase-like orphan receptor 2 (ROR2) has been shown to play opposite roles in the progression of different tumor types. In melanoma, ROR2 was shown to associate with a more invasive phenotype and to contribute to experimental lung colonization. However, the underlying mechanisms regulated by ROR2 have not been elucidated. More importantly, it has no...

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Literature Corpus work: b5213c76-6e90-5c12-b61d-713f0098e7a8
DOI: 10.21203/rs.3.rs-1050315/v1

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