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miR-151a-5p in Neuron-Derived Extracellular Vesicles Mediates Antidepressant Response

2026-08-12

Abstract excerpt

Major depressive disorder (MDD) lacks accessible molecular markers that reflect brain pathology and monitor treatment response. Using the neuron-specific protein SNAP25, we investigated the cargo of neuron-derived extracellular vesicles (NEVs) isolated from plasma in relation to antidepressant treatment and identified miR-151a-5p as a mediator of treatment response, increasing selectively in responders while remai...

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Literature Corpus work
b50cfbd1-52ac-5ce2-ae85-972aafcf685c
DOI
10.64898/2026.08.11.26360193
Open publication

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miR-151a-5p in Neuron-Derived Extracellular Vesicles Mediates Antidepressant ResponseDOI 10.64898/2026.08.11.26360193
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