Article

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

2019-02-08

Abstract excerpt

<h4>ABSTRACT</h4> Streptococcus agalactiae (Group B Streptococcus , GBS) normally colonizes healthy adults but can cause invasive disease, such as meningitis, in the newborn. To gain access to the central nervous system, GBS must interact with and penetrate brain or meningeal blood vessels; however, the exact mechanisms are still being elucidated. Here, we investigate the contribution of BspC, an antigen I/II fa...

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Literature Corpus work: b500f636-e51b-5dbf-a52d-1869f1af4d24
DOI: 10.1101/544395

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