Article
The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates
18 Oct 2010
Abstract excerpt
Streptococcus agalactiae (group B streptococcus; GBS) is a normal constituent of the intestinal microflora and the major cause of human neonatal meningitis. A single clone, GBS ST-17, is strongly associated with a deadly form of the infection called late-onset disease (LOD), which is characterized by meningitis in infants after the first week of life. The pathophysiology of LOD remains poorly understood, but our...
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