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Group B Streptococcal Infection and Activation of Human Astrocytes

1 Jun 2015

Abstract excerpt

BACKGROUND: Streptococcus agalactiae (Group B Streptococcus, GBS) is the leading cause of life-threatening meningitis in human newborns in industrialized countries. Meningitis results from neonatal infection that occurs when GBS leaves the bloodstream (bacteremia), crosses the blood-brain barrier (BBB), and enters the central nervous system (CNS), where the bacteria contact the meninges. Although GBS is known to...

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PMID: 26030618
DOI: 10.1371/journal.pone.0128431

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