Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AURKB drives aggressive phenotype and clinicopathological progression in cholangiocarcinoma.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Sept 2026

Wang Minglong, Shang Peipei, Luo Yanxi, Hu Meidi

Abstract excerpt

OBJECTIVE: This study aimed to explore the role of AURKB (Aurora kinase B) in the progression of cholangiocarcinoma and evaluate its correlation with pathological characteristics, survival, and cellular function. METHODS: We used immunohistochemistry, qRT-PCR, Western blot, CCK-8 cell proliferation assay, scratch assay, colony formation assay, Transwell cell migration assay, lentiviral overexpression and...

Topics

Join the communities discussing this publication.

Apoptosis
Aurora Kinase B
Bile Duct Neoplasms
Cell Movement
Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cholangiocarcinoma

Disease Progression

Source

Identifiers

PMID: 41840316
DOI: 10.1007/s12094-026-04307-7

Genes

AURKB
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AURKB drives aggressive phenotype and clinicopathological progression in cholangiocarcinoma.PMID 41840316Read ↗

AURKB activates EMT through PI3K/AKT signaling axis to promote ICC progressionSemantic proximity Read ↗

AURKB activates EMT through PI3K/AKT signaling axis to promote ICC progressionSemantic proximity Read ↗

Overexpression of Aurora Kinase B Is Correlated with Diagnosis and Poor Prognosis in Hepatocellular CarcinomaSemantic proximity Read ↗

Molecular Pathogenesis of Cholangiocarcinoma: Implications for Disease Classification and Therapy.Semantic proximity Read ↗

AURKB targets DHX9 to promote hepatocellular carcinoma progression via PI3K/AKT/mTOR pathwaySemantic proximity Read ↗

Pathogenesis of CholangiocarcinomaSemantic proximity Read ↗

Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in CholangiocarcinomaSemantic proximity Read ↗

Activation of the PI3K-AKT signaling pathway by SPARC contributes to the malignant phenotype of cholangiocarcinoma cells.Semantic proximity Read ↗

The Advancement of Long Non-Coding RNAs in Cholangiocarcinoma DevelopmentSemantic proximity Read ↗

Comprehensive molecular-clinical profiling of cholangiocarcinoma according to pathologic subtypes.Semantic proximity Read ↗

The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma.Semantic proximity Read ↗

Establishment and characterization of a novel highly aggressive hilar cholangiocarcinoma cell line, CBC3T-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.