Article
SNCA locus Triplication Drives Severe Parkinson’s Disease: Platelet and Blood Expression Profiles Evidence Systemic Involvement
2026-01-21
Abstract excerpt
<title>Abstract</title> <p> Parkinson disease (PD) is increasingly recognized as a multisystem condition with substantial immune involvement. Functional parallels described between neurons and platelets have raised interest in the latter as a window into neurodegenerative disease mechanisms. While most PD cases are sporadic, rarely, mutations or gene dosage increases of <italic>SNCA</italic> cause familial PD....
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Identifiers and source
- Literature Corpus work
- b4be113e-e839-59df-a0d1-de37d784d8be
- DOI
- 10.21203/rs.3.rs-8422817/v1