Article

Histone lysine crotonylation regulates cell-fate determination of neural stem/progenitor cells by activating bivalent promoters

2020-05-27

Abstract excerpt

Histone lysine crotonylation (Kcr), an evolutionarily conserved and widely expressed non-acetyl short-chain lysine acylation, plays important roles in transcriptional regulation and disease development. However, its genome-wide distribution, correlation with gene expression, and dynamic changes during developmental processes are largely unknown. In this study, we find that histone Kcr is mainly distributed in acti...

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Literature Corpus work: b4a98a7d-ea73-5c0d-a11d-c5755a7e3e0c
DOI: 10.1101/2020.05.27.118596

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