Article

Identification of senescence-associated drivers of tumour growth and progression using a novel microarray platform

2025-12-23

Abstract excerpt

Senescence and the senescence associated secretory phenotype (SASP) are implicated in promoting early tumorigenesis but due to the complexity of SASP it has been difficult to identify the responsible factors. We used canonical SASP factors on our microenvironment microarray (MEMA) platform to systematically identify SASP-associated drivers of tumorigenesis in breast and lung cancer cells. We found multiple SASP fa...

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Literature Corpus work: b488c28c-2c2b-52a1-ba9c-72ffc6465107
DOI: 10.64898/2025.12.20.695739

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