Article

Asian Flush Gene Variant Enhances Cellular Immunogenicity of COVID‐19 Vaccine: Prospective Study in the Japanese General Population

2024-08-20

Abstract excerpt

Because we observed a reduced humoral immune response to the COVID-19 vaccine and subsequently discovered a lower susceptibility to COVID-19 in individuals carrying the ALDH2 rs671 variant, we hypothesized that rs671 is beneficial for cellular immunity against COVID-19. Using the IFN-γ enzyme-linked immunospot (ELISPOT) assay, we evaluated cellular immunity before and after COVID-19 vaccination in two subcoh...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b475e07c-e65c-5e0e-b8b4-df9bd7061a98
DOI: 10.20944/preprints202408.1453.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Asian Flush Gene Variant Enhances Cellular Immunogenicity of COVID‐19 Vaccine: Prospective Study in the Japanese General PopulationDOI 10.20944/preprints202408.1453.v1Read

Variant Allele of <em>ALDH2</em>, rs671 Associates with Attenuated Post-Vaccination Response in Anti-SARS-CoV-2 Spike Protein IgG: A Prospective Study in the Japanese General PopulationSemantic proximity Read

Variant Allele of ALDH2, rs671, Associates with Attenuated Post-Vaccination Response in Anti-SARS-CoV-2 Spike Protein IgG: A Prospective Study in the Japanese General PopulationSemantic proximity Read

Asian Flush Phenotype Associated with Protective Properties Against COVID-19: Web-based Retrospective StudySemantic proximity Read

Genetic variation in HLA, IGKV and HHEX loci influence mRNA vaccine-induced long-lasting humoral protection against COVID-19Semantic proximity Read

How could our genetics impact COVID-19 vaccine response?Semantic proximity Read

Germline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicitySemantic proximity Read

Genetic determinants of IgG antibody response to COVID-19 vaccinationSemantic proximity Read

Genetic markers of enhanced functional antibody responses to COVID-19 vaccinationSemantic proximity Read

The humoral and cellular response to mRNA SARS-CoV-2 vaccine is influenced by HLA polymorphisms.Semantic proximity Read

Multi-phasic gene profiling using candidate gene approach predict the capacity of specific antibody production and maintenance following COVID-19 vaccination in Japanese population.Semantic proximity Read

Personalized Health and the Coronavirus Vaccines --Do Individual Genetics Matter?Semantic proximity Read

New genetic associations detected in a host response study to hepatitis B vaccine.Semantic proximity Read