Article
Multi-phasic gene profiling using candidate gene approach predict the capacity of specific antibody production and maintenance following COVID-19 vaccination in Japanese population.
Frontiers in immunology - 1 Jan 2023
Takemoto Yuki, Tanimine Naoki, Yoshinaka Hisaaki, Tanaka Yuka, Takafuta Toshiro, Sugiyama Aya, Tanaka Junko, Ohdan Hideki
Abstract excerpt
Background: Vaccination against severe acute respiratory syndrome coronavirus type 2 is highly effective in preventing infection and reducing the severity of coronavirus disease (COVID-19). However, acquired humoral immunity wanes within six months. Focusing on the different tempo of acquisition and attenuation of specific antibody titers in individuals, we investigated the impact of genetic polymorphisms on...
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