Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure

15 Dec 2023

Abstract excerpt

Antiretroviral therapy (ART) has brought the HIV/AIDS epidemic under control, but a curative strategy for viral eradication is still needed. The cessation of ART results in rapid viral rebound from latently infected CD4+ T cells, showing that control of viral replication alone does not fully restore immune function, nor does it eradicate viral reservoirs. With a better understanding of factors and mechanisms that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38140676
DOI: 10.3390/v15122435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a CurePMID 38140676Read ↗

The role of latency reversal in HIV cure strategiesSemantic proximity Read ↗

Curing HIV: Pharmacologic Approaches to Target HIV-1 LatencySemantic proximity Read ↗

The Current Status of Latency Reversing Agents for HIV-1 RemissionSemantic proximity Read ↗

Forging a Functional Cure for HIV: Transcription Regulators and InhibitorsSemantic proximity Read ↗

Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue ReservoirsSemantic proximity Read ↗

Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing AgentsSemantic proximity Read ↗

A broad drug arsenal to attack a strenuous latent HIV reservoirSemantic proximity Read ↗

HIV-1 Latency and Viral Reservoirs: Existing Reversal Approaches and Potential Technologies, Targets, and Pathways Involved in HIV Latency StudiesSemantic proximity Read ↗

Diverse Impacts of HIV Latency-Reversing Agents on CD8+ T-Cell Function: Implications for HIV CureSemantic proximity Read ↗

New latency-promoting agents for a block-and-lock functional cure strategySemantic proximity Read ↗

Strategies to eradicate HIV from infected patients: elimination of latent provirus reservoirsSemantic proximity Read ↗

Block-And-Lock: New Horizons for a Cure for HIV-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.