Article

Hearing loss promotes schizophrenia-relevant brain and behavioral abnormalities in a mouse model of human 22q11.2 Deletion Syndrome

2019-02-03

Abstract excerpt

<h4>ABSTRACT</h4> Hearing loss has been implicated as a risk factor for schizophrenia, but it is not known whether this association arises from common etiology, top-down influences (e.g., social isolation), bottom-up neurobiological mechanisms, or combinations of these factors. Patients with 22q11.2 Deletion Syndrome (22q11.2DS) have a 25-30% risk of developing schizophrenia, and also suffer frequent hearing loss...

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Literature Corpus work: b448a4a5-d9aa-5eef-9ad8-d5a0f0b440d3
DOI: 10.1101/539650

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