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Article

Pathways to understanding psychosis through rare - 22q11.2DS - and common variants.

Current opinion in genetics & development - 1 Jun 2021

Gur Raquel E, Roalf David R, Alexander-Bloch Aaron, McDonald-McGinn Donna M, Gur Ruben C

Abstract excerpt

The 22q11.2 Deletion Syndrome has significant impact on brain and behavior, with about 25% of individuals developing schizophrenia. The condition offers a model for prospective studies on the emergence of psychosis and advancing mechanistic hypotheses on gene-environment interactions, with magnified power for examining genome-phenome association. Here, we highlight findings that build on the International 22q11.2...

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Identifiers

PMID: 33571729
DOI: 10.1016/j.gde.2021.01.007
PMCID: PMC8728946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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