Article

Endoglin regulates the integrity of the bone marrow vasculature

2024-07-25

Abstract excerpt

Endoglin (Eng) is an accessory receptor for transforming growth factor-β (TGF-β) that is critical for maintaining vascular integrity. Mutations in Eng cause hereditary hemorrhagic telangiectasia (HHT), resulting in arteriovenous malformations (AVMs) and blood abnormalities. Despite the known association between Eng deficiency and AVMs, the underlying mechanisms are unclear. In addition, the role of the bone marrow...

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Literature Corpus work: b44326f9-a228-5cb7-abce-fd7f3b5190c6
DOI: 10.1101/2024.07.24.605039

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