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Article

Endothelial cell biology of Endoglin in hereditary hemorrhagic telangiectasia.

Current opinion in hematology - 1 May 2018

Sugden Wade W, Siekmann Arndt F

Abstract excerpt

PURPOSE OF REVIEW: Mutations in the Endoglin (Eng) gene, an auxiliary receptor in the transforming growth factor beta (TGFβ)-superfamily signaling pathway, are responsible for the human vascular disorder hereditary hemorrhagic telangiectasia (HHT) type 1, characterized in part by blood vessel enlargement. A growing body of work has uncovered an autonomous role for Eng in endothelial cells. We will highlight the...

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Identifiers

PMID: 29438260
DOI: 10.1097/MOH.0000000000000419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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