Article

Clock gene Bmal1 influences the cell cycle of chondrocytes in osteoarthritis

2024-09-26

Abstract excerpt

<title>Abstract</title> <p>Osteoarthritis (OA) is a degenerative disease caused by multiple factors. This study used in vitro and animal models to investigate the connection between the biological clock and cell cycle in osteoarthritic cartilage. The results indicate that the transcription levels of the circadian clock gene Bmal1 exhibit a negative correlation with Mmp13 and positive correlation with Wee1. Thus,...

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Literature Corpus work: b408ac4e-58ac-57c7-bc56-fdc7bfccaae5
DOI: 10.21203/rs.3.rs-4961150/v1

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