Article

Temporal and disease-site specific transcriptional and phenotypic changes in response to neoadjuvant chemotherapy in high-grade serous ovarian cancers

2023-04-27

Abstract excerpt

<title>Abstract</title> <p>Neoadjuvant chemotherapy (NACT) has been known to induce genomic and transcriptomic alterations within tumours. Here, using transcriptome profiling along with histological analysis of pre and post NACT, we show temporal and disease site-specific differences (omentum, ovary and other sites) in high grade serous ovarian cancer (HGSOC) and their association with progression free and overal...

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Literature Corpus work: b38775f1-1760-58d4-9adc-201550fad10b
DOI: 10.21203/rs.3.rs-2840508/v1

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