Article

A workflow for clinical profiling of BRCA genes in Chilean breast cancer patients via targeted sequencing

2024-10-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Breast cancer (BC) is the leading cause of cancer-related deaths among women globally and in Chile. Mutations in the tumor-suppressor genes <italic>BRCA1</italic> and <italic>BRCA2</italic> significantly increase the risk of developing cancer, with the probability rising by more than 50%. Identifying pathogenic variants in <italic>BRCA1</italic> and <italic>BRCA...

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Literature Corpus work: b37aaac0-7339-5181-9a8f-068cbe078584
DOI: 10.21203/rs.3.rs-5284910/v1

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