Article

Short chain fatty acid butyrate promotes virus infection by repressing interferon stimulated genes

2020-02-05

Abstract excerpt

Butyrate is an abundant metabolite produced by the gut microbiota and is known to modulate multiple immune system pathways and inflammatory diseases. However, studies of its effects on virus infection of cells are limited and enigmatic. We found that butyrate increases cellular infection and virus replication in influenza virus, reovirus, and human immunodeficiency virus infections. Further exploring this phenomen...

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Literature Corpus work: b35564ea-bf1c-5077-8eb6-a00ca964a960
DOI: 10.1101/2020.02.04.934919

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