Article
Acetate Triggers Antiviral Response Mediated by RIG-I in Cells from Infants with Respiratory Syncytial Virus Bronchiolitis
2021-09-01
Abstract excerpt
Background: Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice againstRSV A2 strain infection by increasing interferon-β production and expression of interferonstimulated genes (<i>ISGs</i>). However, the role of SFCAs in RSV infection using strains isolated from patients is unknown.<br><br>Methods: We first used RSV clinical strains isolated from infants hospitalized with RSV bronchiolitis...
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Identifiers and source
- Literature Corpus work
- 2a4f68e7-ebad-59f7-af3c-2a77fb5f45c3
- DOI
- 10.2139/ssrn.3915421
