Article

Revolutionizing Detection of Minimal Residual Disease in Breast Cancer Using Patient-Derived Gene Signature

2025-06-04

Abstract excerpt

Many patients harbor minimal residual disease (MRD)—small clusters of residual tumor cells that survive therapy and evade conventional detection but drive recurrence. Although advances in molecular and computational methods have improved circulating tumor DNA (ctDNA)-based MRD detection, these approaches face challenges: ctDNA shedding fluctuates widely across tumor types, disease stages, and histological features...

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Literature Corpus work: b34d9425-6d6d-5ec8-aedd-4b894c726646
DOI: 10.20944/preprints202506.0318.v1

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