Article
Prognostic value of circulating tumor DNA mutation panels to predict early recurrence and survival outcomes in early-stage breast cancer: a systematic review and meta-analysis.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 May 2026
Ali Mohsin, Imran Muhammad, Hussain Jawad, Zakria Muhammad, Abbasi Asma Ehsan, Sultan Aneesa
Abstract excerpt
BACKGROUND: Early-stage breast cancer (BC) shows heterogeneous recurrence risk. Circulating tumor DNA (ctDNA) is promising non-invasive biomarker for minimal residual disease and recurrence prediction, though prognostic performance varies by assay and context. METHODS: Eligible studies on ctDNA-based recurrence and survival were identified through comprehensive searches, quality assessed, and analyzed using...
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