Article

Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

2018-08-09

Abstract excerpt

<h4>SUMMARY</h4> The sarcomatoid variant of urothelial bladder cancer (SARC) displays a high propensity for distant metastasis and is associated with short survival. We report a comprehensive genomic analysis of 28 cases of SARCs and 84 cases of conventional urothelial carcinomas (UCs), with the TCGA cohort of 408 muscle-invasive bladder cancers serving as the reference. SARCs showed a distinct mutational landsca...

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Literature Corpus work: b322cc53-ed9a-5ce0-9275-3e567ebdefa4
DOI: 10.1101/388264

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