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Article

Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer.

Nature reviews. Urology - 1 Jul 2014

Choi Woonyoung, Czerniak Bogdan, Ochoa Andrea, Su Xiaoping, Siefker-Radtke Arlene, Dinney Colin, McConkey David J

Abstract excerpt

Whole-genome analyses have revealed that muscle-invasive bladder cancers (MIBCs) are heterogeneous and can be grouped into basal and luminal subtypes that are highly reminiscent of those found in breast cancer. Basal MIBCs are enriched with squamous and sarcomatoid features and are associated with advanced stage and metastatic disease at presentation. Like basal breast cancers, basal bladder tumours contain a...

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Source

Identifiers

PMID: 24960601
DOI: 10.1038/nrurol.2014.129

Genes

ERBB2
ERBB3
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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