Article

Epigenomic analysis of high-grade T1 bladder cancer reveals subtypes with clinical implications that display extensive intra-tumor heterogeneity with spatial features.

2024-11-11

Abstract excerpt

<title>Abstract</title> <p>High-Grade T1 (HGT1) Non-Muscle Invasive is an early-stage of Bladder Cancer (NMIBC) with an unpredictable relapse and recurrence rate. New biomarkers are needed for patient risk prediction and to determine treatment. Here, we analyze the molecular characteristics of HGT1 NMIBC by combining multi-omics at bulk and single-cell resolution. We have identified two chromatin states that refl...

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Literature Corpus work: b3129bce-4382-5037-8bc9-402da9cdc2f0
DOI: 10.21203/rs.3.rs-5285350/v1

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