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Multi-omics consensus ensemble refines the classification of muscle-invasive bladder cancer with stratified prognosis, tumour microenvironment and distinct sensitivity to frontline therapies

2021-05-31

Abstract excerpt

<h4>ABSTRACT</h4> The molecular classification of muscle-invasive bladder cancer (MIBC) based on transcriptomic signatures has been extensively studied. The complementary nature of information provided by different molecular profiles motivated us to refine MIBC classification by aggregating multi-omics data. We generated a consensus ensemble through ten multi-omics integrative clustering approaches on 396 MIBCs f...

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Literature Corpus work
83e8a1ca-f44c-5124-9481-c8b5db8f4bed
DOI
10.1101/2021.05.30.446369
Open publication

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Multi-omics consensus ensemble refines the classification of muscle-invasive bladder cancer with stratified prognosis, tumour microenvironment and distinct sensitivity to frontline therapiesDOI 10.1101/2021.05.30.446369
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