Article

Potential Role of APOBEC3 Family Proteins in SARS-CoV-2 Replication

2024-06-18

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has acquired multiple mutations since its emergence. Analyses of the SARS-CoV-2 genomes from infected patients exhibit a bias toward C-to-U mutations, which are suggested to be caused by the apolipoprotein B mRNA editing enzyme polypeptide-like 3 (APOBEC3, A3) cytosine deaminase proteins. However, the role of A3 enzymes in SARS-CoV-2 replication remains...

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Literature Corpus work: b2fdc018-a41c-5179-9793-62d6d74c9e62
DOI: 10.20944/preprints202406.1182.v1

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