Article

Association of pronounced Elevation of NET formation and Nucleosome Biomarkers with Mortality in Patients with Septic Shock

2023-06-05

Abstract excerpt

<h4>Background: </h4> Understanding the mechanisms underlying immune dysregulation in sepsis is a major challenge in developing more individualized therapy, as early and persistent inflammation, as well as immunosuppression, play a significant role in pathophysiology. As part of the antimicrobial response, neutrophils can release extracellular traps (NETs) which neutralize and kill microorganisms. However, excessi...

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Literature Corpus work: b2f0692e-8765-5c03-9f59-52fe0989eeb8
DOI: 10.21203/rs.3.rs-3000594/v1

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