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Article

Circulating nucleosomes are associated with mortality in pediatric acute respiratory distress syndrome

29 Apr 2016

Abstract excerpt

Mechanisms underlying pediatric acute respiratory distress syndrome (PARDS) are poorly understood. The recent implication of circulating nucleosomes as pathogenic in sepsis and trauma-associated ARDS in adults led us to investigate the significance of nucleosomes in PARDS. We conducted a prospective, observational study on children with PARDS at the Children's Hospital of Philadelphia between July 2014 and...

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PMID: 27130528
DOI: 10.1152/ajplung.00067.2016

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