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Article

Unraveling NETs in Sepsis: From Cellular Mechanisms to Clinical Relevance

1 Aug 2025

Abstract excerpt

Sepsis is a clinical syndrome characterized by a dysregulated host response to infection, frequently resulting in septic shock and multi-organ failure. Emerging evidence highlights the critical role of neutrophil extracellular traps (NETs) in the pathophysiology of sepsis. NETs are extracellular structures composed of chromatin DNA, histones, and granular proteins released by neutrophils through a specialized...

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Share to Neonatal and Maternal Infections
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PMID: 40806591
DOI: 10.3390/ijms26157464

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