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The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I

2020-05-24

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 infection have caused global pandemic and claimed over 5,000,000 tolls 1–4 . Although the genetic sequences of their etiologic viruses are of high homology, the clinical and pathological characteristics of COVID-19 significantly differ from SARS 5,6 . Especially, it seems that SARS-CoV-2 undergoes vast replication in vivo without being effectively monitored by anti-viral immunity 7...

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Literature Corpus work
b2b6c08b-325e-5829-9cc8-f6d8c759e128
DOI
10.1101/2020.05.24.111823
Open publication

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The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-IDOI 10.1101/2020.05.24.111823
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