Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 ORF8: One protein, seemingly one structure, and many functions

24 Oct 2022

Abstract excerpt

SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. The genome of SARS-CoV-2 encodes nine accessory proteins that are involved in host-pathogen interaction. ORF8 is unique among these accessory proteins. SARS-CoV-2 ORF8 shares a surprisingly low amino acid sequence similarity with SARS-COV ORF8 (30%), and it is presumed to have originated from bat. Studies have shown that ORF8 exerts multiple different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to SARS-CoV-2 detection and testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36353628
DOI: 10.3389/fimmu.2022.1035559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 ORF8: One protein, seemingly one structure, and many functionsPMID 36353628Read ↗

SARS-CoV-2 ORF8: A Rapidly Evolving Immune and Viral Modulator in COVID-19Semantic proximity Read ↗

SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional ConvergenceSemantic proximity Read ↗

SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional ConvergenceSemantic proximity Read ↗

A unique view of SARS-CoV-2 through the lens of ORF8 proteinSemantic proximity Read ↗

SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progressionSemantic proximity Read ↗

Lost in deletion: The enigmatic ORF8 protein of SARS-CoV-2.Semantic proximity Read ↗

The Functional Classification of ORF8 in SARS-CoV-2 Replication, Immune Evasion, and Viral Pathogenesis Inferred through Phylogenetic ProfilingSemantic proximity Read ↗

SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression.Semantic proximity Read ↗

Atypical Divergence of SARS-CoV-2 Orf8 from Orf7a within the Coronavirus Lineage Suggests Potential Stealthy Viral Strategies in Immune EvasionSemantic proximity Read ↗

Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis Mechanisms of SARS-Related CoronavirusesSemantic proximity Read ↗

Structural Analysis of SARS-CoV-2 ORF8 Protein: Pathogenic and Therapeutic ImplicationsSemantic proximity Read ↗

Impairment of antiviral immune response and disruption of cellular functions by SARS-CoV-2 ORF7a and ORF7bSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.