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Article

The SARS-CoV-2 accessory factor ORF7a downregulates MHC class I surface expression

2022-05-30

Abstract excerpt

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in over 500 million infections and more than six million deaths worldwide. Although the viral genomes of SARS-CoV-1 and SARS-CoV-2 share high sequence homology, the clinical and pathological features of COVID-19 differ profoundly from those of SARS. It is apparent that changes in viral genes contribute to the increased...

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Literature Corpus work
dec88b11-f31a-5836-91de-2750a68446e4
DOI
10.1101/2022.05.29.493850
Open publication

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The SARS-CoV-2 accessory factor ORF7a downregulates MHC class I surface expressionDOI 10.1101/2022.05.29.493850
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