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Article

Identification of Sex-Specific Candidate Genes Underlying Childhood Asthma Using Integrative Transcriptomic and Mendelian Randomization Approaches

2025-09-09

Abstract excerpt

<title>Abstract</title> <p>Objective This study aimed to identify key candidate genes underlying sex disparities in childhood asthma. Methods Blood gene expression datasets from children with asthma and healthy controls (GSE27011 and GSE203482) were retrieved from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) between asthma and normal blood samples were identified using limma p...

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Literature Corpus work
b28ffc99-22d0-585f-b1c8-deda6fcf8c92
DOI
10.21203/rs.3.rs-7547685/v1
Open publication

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Identification of Sex-Specific Candidate Genes Underlying Childhood Asthma Using Integrative Transcriptomic and Mendelian Randomization ApproachesDOI 10.21203/rs.3.rs-7547685/v1
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