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Article

Multiomics Approach Identifies Novel Genetic Determinants and Therapeutic Targets for Asthma.

Canadian respiratory journal - 1 Jan 2026

Liu Fang, Cui Hongtao, Mei Yan, Li Keyu, Xu Yan, Li Shuman, Yuan Chao

Abstract excerpt

Asthma constitutes a widespread chronic respiratory disease with multifactorial origins, in which definitive genetic components remain incompletely understood. This investigation synthesized transcriptomic data and Mendelian randomization (MR) to delineate causative genes contributing to asthma predisposition. Evaluation of the GSE43696 cohort disclosed 267 genes displaying expression alterations between healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42133797
DOI: 10.1155/carj/6447989
PMCID: PMC13175393

Genes

DUSP5
FCER1A
LGALS2
SHISA2
USP36
CCR5
CXCL10
CXCL6
GPRIN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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