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Article

Identification of allergic rhinitis-related genes and mediating immune cells based on cis-eQTL: A Mendelian randomization study.

Medicine - 17 Apr 2026

Peng Jianghua, Yan Xin, Shen Mingzhu, Xuan Junmei, Chen Suhua

Abstract excerpt

In this study, we aimed to identify genes causally associated with allergic rhinitis (AR) by extracting cis-expression quantitative trait loci (cis-eQTL) as instrumental variables using the Mendelian randomization (MR) method, and further explore the role mechanisms of gene-related immune cells in AR. All genome-wide association study (GWAS) and eQTL data were from public databases. Genes causally associated with...

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Topics

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Share to AR gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

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Share to Polymorphism, Single Nucleotide

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Share to Rhinitis, Allergic

Share to T-Lymphocytes, Regulatory

Source

Open in PubMed Open full text

Identifiers

PMID: 41995544
DOI: 10.1097/MD.0000000000048349
PMCID: PMC13095335

Genes

AR
TNFRSF18
CD4
CD44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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