Article
Role of epidermal primary cilia in the homeostasis of skin and hair follicles.
Development (Cambridge, England) - 1 May 2011
Croyle Mandy J, Lehman Jonathan M, O'Connor Amber K, Wong Sunny Y, Malarkey Erik B, Iribarne Daniela, Dowdle William E, Schoeb Trenton R, Verney Zoe M, Athar Mohammad, Michaud Edward J, Reiter Jeremy F, Yoder Bradley K
Abstract excerpt
Skin and hair follicle morphogenesis and homeostasis require the integration of multiple signaling pathways, including Hedgehog (Hh) and Wingless (Wnt), and oriented cell divisions, all of which have been associated with primary cilia. Although studies have shown that disrupting dermal cilia causes follicular arrest and attenuated Hh signaling, little is known about the role of epidermal cilia. Here, epidermal...
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